Wollmuth Hsieh

Publications

Publications (last 4 years)

Henry, D.*, C. Joselevitch*, G. G. Matthews, and L. P. Wollmuth.  Expression and distribution of synaptotagmin family members in the zebrafish retina.  The Journal of Comparative Neurology. In press. BIORXIV/2020/239814.   *Authors contributed equally.  doi: https://doi.org/10.1101/2020.08.06.239814.

Amin, J. B.*, A. Gochman*, M. He, N. Certain, and L. P. Wollmuth (2021) NMDA receptors require multiple pre-opening gating steps for efficient synaptic activity. Neuron. 109: 488-501. doi: 10.1016/ j.neuron.2020.11.009. (PMCID: PMC7864875).    *Authors contributed equally.

Baez, A., T. V. Brunt, G. Moody, L. P. Wollmuth, and H. Hsieh (2020) Voltage dependent allosteric modulation of IPSCs by benzodiazepines.  Brain Research. Jun 1;1736:146699. doi: 10.1016/j.brainres.2020.146699.

Zoodsma, J. D.*, K. Chan*, A. A. Bhandiwad, D. Golann, G. Liu, S. Syed, A. Napoli, H. Burgess, H. Sirotkin‡, and L. P. Wollmuth‡. (2020) A model to study NMDA receptors in early nervous system development. The Journal of Neuroscience. 40:3631-3645. (PMCID: PMC7189761).    *Authors contributed equally.  ‡co-senior authors.

Chan, K.*, J. Nestor*, T. S. Huerta, N. Certain, G. Moody, C. Kowal, P. T. Huerta, B. T. Volpe, B. Diamond‡ and L. P. Wollmuth‡ (2020) Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory. Nature Communications, 11:1403(2020). (PMCID: PMC7075964).   *Authors contributed equally.  ‡co-senior authors.

Li, J., J. Zhang, W. Tang, R. K. Mizu, H. Kusumoto, W. XiangWei, Y. Xu, W. Chen, J. B. Amin, C. Hu, V. Kannan, S. R. Keller, W. R. Wilcox, J. R. Lemke, S. J. Myers, S. A. Swanger, L. P. Wollmuth, S. Petrovski, S. F. Traynelis, and H. Yuan (2019) De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases. Human Mutation. 40:2393-2413. (PMCID: PMC6874887).

Vaithianathan, T, L. P. Wollmuth, D. Henry, D. Zenisek, and G. G. Matthews (2019) Tracking newly released synaptic vesicle proteins at the active zones of ribbon synapses. iScience. 10:10-23. (PMCID: PMC6598641).

Esmenjaud, J.-B., D. Stroebel, K. Chan, T. Grand, M. David, L. P. Wollmuth, A. Taly, and P. Paoletti (2019) An inter-dimer allosteric switch controls NMDA receptor activity. EMBO Journal. 38:e99894.  (PMCID: PMC6331725)

Ferrer, C., H. Hsieh, and L. P. Wollmuth (2018) Input-specific maturation of NMDAR-mediated transmission onto parvalbumin-expressing interneurons in layers 2/3 of the visual cortex. Journal of Neurophysiology. 120:3063-3076. (PMCID: PMC6337035)

Amin, J, X. Leng, A. Gochman, H-X. Zhou, and L. P. Wollmuth (2018) A conserved glycine harboring disease-associated mutations permits NMDA receptor slow deactivation and high Ca2+ permeability.  Nature Communication. 9:3748(2018).  (PMCID: PMC6138751) 

Reviews (last 4 years)

Wollmuth, L. P., K. Chan, and L Groc. (2021) Diverse and complex modes of action of anti-NMDA receptor autoantibodies. Neuropharmacology, 194:1-17.

Amin, J. B.*, G. Moody*, & L. P. Wollmuth (2021) From bedside-to-bench: What disease-associated variants are teaching us about the NMDA receptor. The Journal of Physiology. Invited review. 599(2):397-416. (PMCID: PMC7483363)  *Authors contributed equally.

Wollmuth, L. P. (2019) Prying open a gate in glutamate receptor. Preview. The Journal of General Physiology. 151:396-399. (PMCID: PMC6445587)

Hansen, K. B., F. Yi, R. E. Perzyk, H. Furukawa, Wollmuth, L. P., A. J. Gibb, and S. F. Traynelis (2018) Structure, function, and allosteric modulation of NMDA receptors.  Journal of General Physiology.  150:1081-1105. (PMCID: PMC6080888)

Amin, J. B. and L. P. Wollmuth (2018) A swiss army knife for targeting receptors. Insight article.  eLife. 24:7 (PMCID: PMC5967861)

Wollmuth, L. P. (2018) Ion permeation in ionotropic glutamate receptors: Still dynamic after all these years.  Current Opinion Physiology.  2: 36-41.  (PMCID: PMC5875445)

H-X. Zhou, and L. P. Wollmuth (2017) Advancing NMDA receptor physiology by integrating multiple approaches. Trends in Neuroscience. 40(3): 129-137.  (PMCID: PMC4457189)